Definition
Translation
Definition of first-pass effect - Reverso English Dictionary
Noun
pharmacologyTECH. reduction of drug concentration before systemic circulationTECH.
- The first-pass effect reduces the drug's bioavailability.
- Doctors must consider the first-pass effect when prescribing medication.
- The first-pass effect can alter the expected outcome of the drug.
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Expressions with first
arrange something at the beginning of a sequence
He put the most important task first on his list.
give in or show weakness before the other side
He didn't want to blink first during the tense meeting.
time when light first appears in the morning
We set out on our hike at first light.
introduce the first point or start the first action before others
First off, we need to discuss the budget before proceeding.
immediately upon seeing something or someone
She fell in love at first sight.
address important tasks before others
First things first, finish your homework before playing.
persistence is important in the pursuit of success
If at first you don't succeed, try again.
moving while the vehicle is set to its lowest gear
He drove in first gear up the steep hill.
take the first step in a process
He made the first move in negotiating the deal.
express conditional death happening before others in a situation
He said he would die first if the disease worsened.
allocated in order of arrival or request
Tickets are available on a first-come-first-served basis.
in an impulsive manner without prior thought
She tends to act first, think later in emergencies.
on first seeing someone or something immediately
At first glance, the painting looks simple.
indicate the first action or event in a sequence
First up, we will discuss the project goals.
polite gesture to let women go ahead
He held the door open and said 'ladies first'.
to take quick action without checking details first
He tends to shoot first and ask questions later in meetings.
act immediately without checking facts or reasons first
He shot first and asked questions later in the meeting.
initiate physical conflict by hitting first
He decided to strike the first blow in the brawl.
act self-righteously in accusing another person
She cast the first stone, ignoring her own mistakes.
cause the first injury in a fight or battle
He managed to draw first blood in the boxing match.
act decisively without gathering all information
In negotiations, he tends to shoot first, ask questions later.
take action immediately without prior deliberation
In emergencies, they act first and question later.
from the original source or personal experience
She learned about the incident at first hand from the witnesses..
successfully on the first attempt
He hit the target at the first shot.
Expressions with pass
move past something or someone
I watched the cars pass by the window..
deliver a message or item to someone
She will pass along the invitation to him.
show or share something among a group
He wanted to pass around the photo to see everyone's reactions..
die, especially in a gentle or euphemistic way
Her grandmother passed away last year..
attempt to move the ball to a teammate in sports
She managed to make a pass to her teammate, securing the goal..
transfer something to the next generation
The recipe was passed down from my grandmother.
give something you have to another person
Please read the note and pass it on.
convey information or a message to someone
Please pass on the news to your friends.
give something to someone else
She will pass on to him the message.
distribute something to a group of people
The teacher passed out the exams to the students..
move across or above
The plane will pass over the city at noon..
distribute something to each person in a group
Please pass round the snacks to everyone.
move past someone without stopping or noticing
The cyclist passed the old man by without a word.
spend time doing something while waiting or relaxing
We played cards to pass the time.
refuse to take an opportunity offered
I can't pass up this job offer.
endure until a weather storm ends
We decided to wait for the storm to pass before leaving.
undeserved forgiveness or allowance for a mistake or fault
Despite his errors, he received a free pass from criticism..
be excused from a responsibility or obligation
He got a pass on the homework assignment.
permit to leave class during school hours
She showed her hall pass to the teacher.
firm refusal or strong unwillingness to accept or do something
When offered broccoli, he gave a hard pass.
present something false as genuine
He tried to pass off the fake painting as real..
present someone or something as different, to trick others
She tried to pass off as a doctor to enter the ward.
give responsibilities or knowledge to someone else
He decided to retire and pass the torch to his daughter..
succeed in a test or exam with high marks
She studied hard and passed with flying colours.
Expressions with effect
intended to produce a reaction
She laughed loudly for effect, hoping to lighten the mood.
situation where one event causes many others
The new policy had a ripple effect on the economy.
situation where something grows quickly from small beginnings
The snowball effect made the problem much bigger.
start working or begin to have the planned effect
The new law will take effect next month.
producing intense excitement and a strongly charged feeling in the room
When she sang, the effect was electric and everyone held their breath.
causes results that grow larger and stronger over time
One missed payment can have a snowball effect on your finances.
behaving in a way to impress others
His speech was just posturing for effect, not genuine concern.
spread of information through informal workplace chats
The water cooler effect helps news travel fast in the office.
spread influence or impact widely
The new policy created a ripple effect throughout the entire organization.
for all practical purposes or in practice
In effect, the new policy changes nothing.
indicates when a change begins
The new rules will go into effect on Monday.
cause something to grow quickly and get bigger over time
The rumor has a snowballing effect on the community.
series of events caused by one initial action
The new law had a knock-on effect on the economy.
producing a successful result
She used her skills to good effect in the project.
with minimal impact or influence
The new policy was implemented, but to little effect.
without any impact or influence
The speech was delivered passionately, but to no effect.
frequent fluctuations in performance or behavior
The team's yo-yo effect made it hard to predict their success.
benefit gained from association with successful person
The candidate won due to the coat-tail effect of the popular president.
benefit gained from association with successful person
She got the job through the coattails effect of her famous mentor.
begin to be applied or enforced
The new regulations will come into effect next year.
series of events resulting from one initial event
Her decision to quit had a domino effect on the team.
cause a series of indirect effects
The new policy will have a knock-on effect on employment.
people judged by one good or bad trait
The horns and halo effect influenced the teacher's opinion.
small actions causing large consequences
The butterfly effect suggests that a butterfly flapping its wings can cause a tornado.
Terms related to first-pass effect
💡 Terms in the same lexical field: analogies, antonyms, common collocates, words with same roots, hypernyms…
View all translations of first-pass effect
✨Click below to see the appropriate translations facing each meaning.
- French:effet de premier passage, ...
- German:First-Pass-Effekt, ...
- Italian:effetto di primo passaggio, ...
- Spanish:efecto de primer paso, ...
- Portuguese:efeito de primeira passagem, ...
- Chinese:首过效应, ...
- Japanese:初回通過効果, ...
- Arabic:تَأْثِير المُرور الأَوَّل, ...
- Hebrew:אֶפֶקְט הַמַּעֲבָר הָרִאשׁוֹן, ...
- Russian:эффект первого прохождения, ...
- Ukrainian:ефект першого проходження, ...
- Hindi:पहले-पास प्रभाव, ...
- Bengali:প্রথম-পাস প্রভাব, ...
- Catalan:efecte de primer pas, ...
- Czech:efekt prvního průchodu, ...
- Danish:første-passage-effekt, ...
- Dutch:levermetabolisme, ...
- Greek:πρώτη διέλευση, ...
- Hungarian:first pass effektus, ...
- Khmer:ឥទ្ធិពលឆ្លងកាត់ដំបូង, ...
- Korean:초회 통과 효과, ...
- Persian:اثر عبور اول, ...
- Polish:efekt pierwszego przejścia, ...
- Portuguese (BR):efeito de primeira passagem, ...
- Romanian:efect de primă trecere, ...
- Swedish:första-passage-effekt, ...
- Thai:ผลกระทบจากการผ่านครั้งแรก, ...
- Turkish:ilk geçiş etkisi, ...
- Vietnamese:hiệu ứng vượt qua đầu tiên, ...
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